Documenting the tech worker movement

Despite the “dot-com crash” in 2000, the tech industry remained an attractive career destination for many who believed technology represented the future. The digital age — defined by global connectivity and computers — had firmly taken hold, and over time, the tech industry emerged as a dominant force in the labor market. High-paying jobs for engineers, designers, and professionals across a wide range of fields became increasingly common. 

MIT PhD student JS Tan SM ’22 was among those who, upon graduating from Brown University and Rhode Island School of Design in 2015, joined the tech industry. 

“A lot of us had this idea that technology, and in particular the technologies related to the internet, had the potential for bringing about a more progressive version of the world,” Tan says. 

Google echoed this ethos to its employees with its once-famous motto, “don’t be evil,” as their informal corporate philosophy and code of conduct guideline. They’ve since dropped the tagline.

But in time, particularly with the start of the first Trump administration, some tech industry employees found themselves questioning if their employers were really intent on supporting policies to support a more democratic world. According to Tan, their willingness to publicly oppose their employers’ actions — at first successfully — is currently experiencing an anti-worker backlash. 

Now, Tan and his former tech industry colleague Clarissa Redwine have published a book on the rise and fall of the tech worker labor movement. “Against Tech Oligarchy: Worker Resistance in the World’s Most Powerful Industry” (Haymarket Books, 2026) chronicles how tech workers organized themselves, the effective strategies they used, and the effect the movement had on Silicon Valley labor politics over the past decade.

Documenting a movement from within

In 2017, Tan was working for Microsoft and Redwine for Kickstarter, when President Donald Trump signed an executive order suspending entry into the United States for nationals from seven predominantly Muslim countries for 90 days, and suspending Syrian refugees from entering the country indefinitely. 

“As a whole, I think the tech sector really pushed back against this,” says Tan. “[OpenAI co-founder] Sam Altman participated in protests of this ban at the airport. In fact, the day before he joined these protests, he wrote in his blog that the tech industry needed to take a stand against the Trump administration, and particularly its immigration policies.” 

Altman’s Jan. 28, 2017, blog post read, in part, “Tech companies go to extraordinary lengths to recruit and retain employees; those employees have a lot of leverage. If employees push companies to do something, I believe they’ll have to. At a minimum, companies should take a public stance. But talking is only somewhat effective, and employees should push their companies to figure out what actions they can take.”

Tan says Altman’s words inspired tech workers across the industry to publicly voice their opposition and “push for the values they believed in.” For the next several years, workers staged walkouts and protested their employers’ contracts with U.S. military and immigration enforcement agencies, as well as workplace policies they considered sexist. 

“That was a time in which a lot of tech workers felt that their companies were walking back the values that they had initially promised,” says Tan.

Their objections initially met with some success. In 2018, following protests by Google employees, the company decided not to renew its contract for Project Maven, a Pentagon initiative using artificial intelligence to analyze drone surveillance footage. Nearly 4,000 employees signed an open letter to their CEO stating, “Google should not be in the business of war.”

Fast forward eight years. Earlier this year, more than 600 employees signed an open letter urging Google’s CEO to reject classified AI work with the Pentagon, citing concerns about potential uses including lethal autonomous weapons and domestic surveillance. 

“The way Google responded to them this time was to say, basically, ‘Too bad, we’re committed to working with the Pentagon,’” says Tan. “So, there is this kind of shift as to how Google is positioning itself politically, as well as to their employees.”

What happened to the tech industry employee leverage? 

Tan’s book outlines several events that he argues have negatively impacted their formerly strong influence. First, following interest rate hikes in 2022, the tech industry lost hundreds of billions in market valuation and set out to cut costs, the most significant of them being the expensive salaries of their employees. In other words, the labor market soured on tech workers, giving employers opportunity to wrest back control, Tan suggests. 

Second, he points to the drastic effect of agentic AI coding systems on the nature of their work, arguing that these tools have deskilled workers and made everyone much more worried about job security.  

“Tech workers had to face these shocks on their own. With a union or some ability to coordinate across workers and bargain as a group, they might’ve had more power to actually push back,” says Tan.  

Documenting the past to support the future

Tan enrolled at MIT in 2020, earning a master’s degree at the MIT Media Lab. He is currently a doctoral student in the Department of Urban Studies and Planning with a focus on the political economy of the tech sector.

At various points in their careers, Tan and his co-author had been involved with organizing in the tech sector. Redwine was a prominent organizer in the union drive at Kickstarter. She was fired from the company in 2019; Redwine said her dismissal was retaliation for her organizing activity, while Kickstarter denied that claim. One reason Tan and Redwine wrote this book is because they saw that the bandwidth for labor organizing among tech workers had hit a new low. 

“Tech workers want to have a say over the way their technologies are designed,” says Tan. “They want to be able to push for the right guardrails around technologies that they’re building. We wanted to use this book as an opportunity to analyze why it was that, within eight years, the tech worker movement had sort of fallen into this state of paralysis.”

They began writing the book in 2024, reliving the highs and lows of the past decade. This is Tan’s first book. He says writing it was an “exhilarating experience” and one that he profoundly enjoyed.

“It’s why, in part, I’m drawn to academia. To a large extent, I believe in the power of research and of writing. To have the opportunity to do this about a subject that I care deeply about has been an amazing experience.”

A book launch and discussion about “Against Tech Oligarchy,” co-hosted by the Department of Urban Studies and Planning, will take place on Oct. 26.

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The next generation’s guide to the new space economy

On the first day of class 16.445J/STS.468J (Entrepreneurship in Aerospace and Mobility Systems), David Mindell, MIT professor of aeronautics and astronautics (AeroAstro) and the Frances and David Dibner Professor of the History of Engineering and Manufacturing, asked his students to take a look at an image of a textbook. The cover featured a bright and inspiring collage of rockets, planets, and all manner of futuristic air- and spacecraft. The title: “Entrepreneurship in Aerospace: A Guide for Founders and Investors.”

“This is the most up-to-date guide on the topic,” Mindell said, describing the book’s treatment of the concepts and procedures involved in innovating in aerospace, an industry experiencing a renaissance of entrepreneurship led by venture-backed startups and rapid innovation, and one that, whether or not we realize it, we all depend on every day. 

Konark Chopra, a graduate student in MIT’s Leaders for Global Operations Program, raised his hand. “Sounds great — how can we get a copy?”

“It doesn’t exist,” replied Mindell. “You’re going to write it this semester.”

After conducting over 50 interviews with founders, operators, engineers, and investors across the aerospace industry, the class pulled it off. The 100-page industry report, titled “Entrepreneurship in Aerospace,” provides comprehensive insight into what it actually takes to build an aerospace venture today, and makes predictions about what is needed in the near future.

The challenge to produce the report was inspired by the bestselling guide “Disciplined Entrepreneurship: 24 Steps to a Successful Startup,” by Bill Aulet, professor of the practice in the MIT Sloan School of Management and managing director of the Martin Trust Center for Entrepreneurship. Originally published in 2013, the book provides an outline for entrepreneurs in any industry to cultivate skills for success. “Entrepreneurship in Aerospace” builds on Aulet’s framework to provide an industry-specific guide. “Aerospace is its own special industry with a unique set of constraints and aspirations,” says Mindell.

“Putting together this report let the students learn what they won’t get from a regular class about aerospace entrepreneurship,” he says. “This is the view of the industry from the young people building its future. I’m incredibly proud of what they’ve accomplished.”

Betting on the known unknowns

During spring 2026, while the class was in session, major developments were shaping the aerospace sector, from NASA’s Artemis II mission to SpaceX’s launch of what would become the largest initial public offering in history. “The entire industry landscape shifted like crazy during the semester,” says Mindell, as just one of the reasons that the report was especially timely. 

The report argues that the volume of capital, talent, and policy attention directed toward aerospace is “structurally different from any prior point in the industry’s history,” creating a pivotal moment for the next generation of entrepreneurs and investors.

The report further outlines five predictions about the new space economy: terrestrial infrastructure for compute, manufacturing, and energy will move off-world; autonomous systems, robots, and humans will continue to work together, but with humans in a supervisory capacity; venture capital investment will run ahead of economic justifications; government investment will become the fastest way for young companies to fundraise; and that we are years away from a global regulatory framework for space companies to operate within. Each prediction, or “bet,” includes a section on “where serious people disagree,” laying out relevant counterarguments to their conclusions.

As a guide, the report also translates its findings into practical tools, including a diagnostic for determining how many independent breakthroughs a company needs to succeed. “One of my favorite tools from the report is the miracle count,” says Chopra. “If your company needs one breakthrough to work, that’s a venture bet. If it needs three, that’s a research project pretending to be a startup.”

The report’s findings were informed both by existing research and by interviews with current aerospace professionals. Students were graded, in part, on how many people they spoke with. Their interviews focused on what excites people about the industry, reasons for their optimism (or pessimism), and how people are working within their organizations to address the challenges they see. 

The experience also allowed the students to expand their professional networks, practicing a core entrepreneurial skill while gaining insider perspectives.

“We sought out people from different corners of aerospace and were always asking, ‘Who else should we talk to?’” says Nicole Lee, a graduate student in AeroAstro. “Not only was I able to reconnect with people in my own network, but I got to introduce classmates to those contacts, and then benefit from the networks they brought in, too. That exchange was a big part of what made the interview process, and the class, so special.”

Engineers as entrepreneurs

The report’s authors — 16 classmates from the Department of Aeronautics and Astronautics, MIT Sloan School of Management, and Wellesley College — bring a range of academic backgrounds and career ambitions to the project, using those different perspectives to connect the realities of aerospace engineering with the economic forces impacting the industry. Their research interests and experiences range from spacecraft propulsion and human spaceflight to investment banking and military operations. Collectively, they have worked across organizations like NASA, SpaceX, Blue Origin, Boeing, and a range of startups.

“What I’ll remember most is the team,” says Chopra. “Everyone showed up with their own wisdom and a willingness to challenge each other, learn from each other, and simply have fun. Those are the teams we hope to keep building with.” 

For Lee, those industry experiences support the report’s predictions about where the field itself is headed. “Entrepreneurship in space is going to involve a much broader group of founders, engineers, researchers, policymakers, and operators,” says Lee. “Everyone working in space can take something away from understanding the entrepreneurial mindset and the cultural shift we’re seeing in commercial space. A much wider range of people will be shaping entrepreneurship in the future. I think that shift has already started with us.”

Mindell sees value in that entrepreneurial mindset, regardless of whether the students go on to found companies of their own. “I don’t know if every student in this class is going to found their own company, and I don’t expect them to, but I do expect them to drive their own careers forward,” he says. “And I think for the moment we’re at, providing that opportunity is the best thing MIT can be doing for our students.”

For Chopra, who has had his sights set on founding an aerospace company for as long as he can remember, the findings from the report are immediately applicable. “The heart of a business, a sustainable business, is the demand. What do the customers want? Sure, I could build cool technology, but if we don’t have anyone buying it, it’s a project, not a company.”

Now armed with a clear and evidence-backed picture of the landscape, Chopra wants the report to generate even more activity across the industry. “If our industry report inspires one person to go out and found a company, or invest in a company, or even think about entrepreneurship in aerospace, it’s a pretty big win.”

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MIT class project turns into an FDA-cleared treatment for tremors

In 2017, a man named Michael walked onto stage in front of a packed Kresge Auditorium at MIT and attempted to draw a spiral, a common test doctors use to diagnose Parkinson’s disease. His tremors, caused by the disease, made the exercise difficult. 

Then, Michael put on a wristband device made by a team of MIT students as part of 2.009 (Product Engineering Processes), who were presenting their prototype that evening.

Michael pressed a button and the device produced a subtle vibration. The vibration sent signals up his wrist and into his brain. His tremors dramatically decreased, and within seconds he was able to draw the spiral with much more precision, to a roaring ovation from the audience.

“When this device is turned on, I feel like I used to feel when I didn’t have Parkinson’s disease,” Michael told the crowd. “It’s an amazing, amazing feeling.”

The performance was so impressive that the student team received requests from classmates and others asking where they could buy the device for family and friends living with tremors. Unfortunately, the students had to explain there was only one — for the time being.

The event set off a near decade-long journey that began by leveraging MIT entrepreneurial resources like MIT Sandbox, MIT FUSE, and the MIT Venture Mentoring Service. In 2020, the student team turned into an official company, Encora Therapeutics. But there were still dozens of hardware iterations ahead. Then there were clinical trials. In one trial, 78 percent of patients reported benefits after 90 days of home use.

This February, nine years after Michael’s brave demonstration, all that work finally paid off: The FDA cleared Encora’s device to help adults with essential tremor, a condition similar to Parkinson’s that causes shaking, often in the hands. 

“It’s been a long and difficult — very difficult — journey, but also very rewarding, especially when we get feedback from patients,” says Daniel Carballo ’18, SM ’20, an Encora co-founder and vice president of strategy. “We hear stories from patients about how they’ve struggled with their condition and how much they benefit from this. It reminds us why we keep going.”

From classroom to commercialization

The three founders of Encora who are still with the company are Carballo, Allison Davanzo ’18, and Kyle Pina ’18. They were each seniors in 2017 when they enrolled in 2.009, MIT’s popular product-design class.

The semester began with a brainstorming session in which groups of about 17 students were asked to come up with dozens of potential product ideas. Carballo proposed a wearable device that used mechanical vibration to send signals to the brain to reduce tremors. The initial idea was to help patients with Parkinson’s disease.

“It was one of hundreds of throwaway ideas,” Carballo recalls. “The initial concept was inspired by classes I had taken in robotics around neural control of movement. I had a preliminary understanding of how an electromechanical device might interact with the body’s control systems and feedback loops that control movement to relieve pathological control of movement.”

The team eventually whittled their long list of ideas down to a few. Carballo’s idea was finally selected by a vote of 16-1 — with Carballo the only dissenting vote.

“I tried to explain to the team that this was so far-fetched that there was no way, in one semester, we would be able to make anything,” Carballo recalls. “Thankfully, I got outvoted.”

Through most of the semester, Carballo’s pessimism looked justified. At every class milestone, the team lagged behind other teams. Then, the week before final presentations, they met Michael, whose severe hand tremors were the result of early-onset Parkinson’s.

“He was a home renovator, so he worked with his hands, but his tremors had progressed to the point that he struggled to turn a screwdriver, use a drill, or even fill out paperwork,” Carballo recalls. “He had become reliant on his wife and daughter not only to run his business, but to help him with everyday activities.”

By this point, the 2.009 team had a prototype that would vibrate to send mechanical feedback to the brain. Carballo described it as “a foamcore box with a Raspberry Pi chip and some wires coming out.” When Michael put on the device and turned it on, his tremors dramatically decreased.

“It was like a light switch turned on and his tremors stopped,” Carballo says. “His wife and daughter started crying. A week later, he was gracious enough to repeat the process on stage for the final presentations.”

The presentation — and the outpouring of interest from people who wanted it for loved ones with Parkinson’s — made the team determined.

“It showed us there were a lot of people with this problem that could really benefit from this,” Carballo says. “A subset of the team became possessed. It would have been such a shame to know this could exist and to have it never leave the classroom.”

Some team members began using MIT’s entrepreneurial resources to commercialize the technology, initially focusing on Parkinson’s. They ran their first clinical trial with 20 Parkinson’s patients in 2022 in collaboration with MassGeneral Brigham. But they soon learned more patients are living with essential tremor.

“It was a greater unmet need,” Carballo says. “There are a lot of drugs being developed for Parkinson’s disease, but essential tremor hasn’t experienced that same innovation.”

Today scientists think tremor is caused by malfunctioning signals in the regions of the brain responsible for interpreting sensory input and coordinating movement.

“In these diseases, neurotransmitter deficiencies result in this pulsed signaling in the brain that manifests as tremors that are basically pulsed motor outputs,” Carballo says.

One current approach to target those signals is surgery that involves drilling holes in the skull to insert electrodes that drive new electrical patterns in the brain. Encora’s watch-like product targets the same brain regions with mechanical vibrations at the wrist.

“We’re applying mechanical stimulus, basically vibration, to stretch receptors in the wrist, which tell your body where it is in space,” Carballo explains. “The stimulation causes the receptors to activate and send a patterned signal to peripheral nerves of the wrist, that then carry the signal to the peripheral nervous system and into the central nervous system, to the same regions of the brain targeted by surgery.”

In 2024, Encora ran a randomized control trial with 47 patients living with essential tremor. Last year, the team ran a 59-person trial where patients used the devices at home. In both trials, more than 70 percent of patients experienced meaningful improvement.

The results were promising enough to gain what’s known as 510(k) clearance from the FDA for use as a medical device, in February of this year.

Helping patients

Most patients see rapid benefit when using Encora’s device. Patients have described the device as life-changing. Some say it allows them to do tasks they haven’t been able to do in years.

“We see some patients using the device 12, 14 hours a day,” Carballo says.

Today, Encora is focused on building a national sales force and working to secure coverage from insurers. As the company ramps up production, the product will finally become available for patients who qualify.

Further down the line, Encora hopes to fulfill its original mission of helping mitigate tremors in patients with Parkinson’s. Carballo believes the approach also holds promise for many other patients.

“There is a surprisingly long list of diseases that this could work for,” Carballo says.  “The most obvious are neurological movement disorders, but the bigger picture of wearable neuromodulation is a rapidly growing field that has seen therapeutic benefit across a broad range of diseases. We see this as a platform technology.”

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New tool lets users repair AI-generated 3D models, then fabricate them just the way they want

“What you see is what you get” is a guiding principle for many software engineers — create programs where the content you’re editing looks the same as the final product. But when you’re using generative artificial intelligence systems to 3D print, say, a mug, you’ll likely get a cup that can’t hold your coffee. Why is that?

The issue is that AI models understand how an object should look, but not how it works, leading to impractical designs that undermine an item’s intended use. Even if you want to fix these errors, the models are typically hard to edit, especially for users new to 3D design.

A new approach called “InstructMesh” makes it much easier to design and print household items, accessories, and robots that work in the real world. The design software, which was developed by researchers at MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL), Google, and Northeastern University, can be prompted to generate a 3D design for a pair of glasses, for instance, and users can then highlight specific parts of the blueprint they’d like refined before 3D printing. It’s an AI-driven interface designed to understand how these designs should look and which edits experts and novices alike want to make, helping them create the objects they actually want to see.

CSAIL researchers used InstructMesh to put a personalized, creative spin on otherwise regular items. For example, the tool produced a mug that appears to be enveloped by a dragon, with its tail being the handle. It also fabricated a shiny blue whistle resembling a shell and a pair of glasses with butterfly wings spreading out just above the lens. Getting even more creative, it made an octopus-like dispenser, with liquids flowing out of each tentacle to distribute drinks into several cups at once.

What makes InstructMesh so adept at following such unique prompts? It pairs Microsoft’s TRELLIS system, which creates 3D models from text and image prompts, with the large language model (LLM) GPT-4, which supports ChatGPT — in other words, visual and textual knowledge combined.

“We wanted to bring together the talents of 3D generators and the reasoning skills of LLMs in an interactive space to make objects that people actually want,” says Faraz Faruqi SM ’22, PhD ’26, lead author on a paper presenting the project, graduate of the Department of Electrical Engineering and Computer Science, and recent CSAIL affiliate. “Language models are great at text and images, while TRELLIS’s talent lies in its ability to create 3D models, since it’s seen so many.”

InstructMesh’s strengths come in handy in other, more surprising areas. MIT scientists used the program to fabricate a knee brace that looks like denim to match a patient’s jeans. InstructMesh can even help create robots — that is, clever enclosures that house wireless components. The researchers made a “bristle bot” that resembles a colorful shrimp to demonstrate this. It has a motor hidden inside, and when switched on, it can slide across surfaces, sort of like a wind-up toy.

Faruqi and his colleagues found that InstructMesh could easily make their desired items. But what would someone who’s never 3D modeled anything think of their program? And could they really detect design flaws before fabrication?

The team has TRELLIS recreate popular 3D models found on Thingiverse, a platform home to millions of 3D printable models, to help them find out. Nearly 80 percent of the models it generated were structurally flawed in some way. CSAIL researchers then asked novices to identify and fix these issues in InstructMesh — and they were able to do both around 90 percent of the time, as reviewed by an expert. What these newcomers lacked in expertise, they made up for in intuition.

InstructMesh scaffolds the actual modeling process, which previously required domain expertise in 3D modeling tools. “With manipulation happening in the latent space of the generative model, InstructMesh supports natural language description of issues, and creates interpretive changes in the geometry for the user to evaluate and approve,” says Faruqi. 

Users then created items resembling things like phone stands and vases, noting that InstructMesh was easy to use. They also found that InstructMesh enabled them to express a wide range of ideas, while the sliders gave them more precision to make certain tweaks, such as enlarging or extruding a particular part of the model.

“The users got what they prompted for and easily tweaked designs where needed,” adds Faruqi. “What they saw is what they got, and the items worked as advertised, so to speak.” 

While users enjoyed using the InstructMesh, Faruqi has an even grander vision for the project. He now works at Google, where he may soon incorporate InstructMesh into an augmented reality (AR) platform. The idea: Prompt the system by explaining what you need using the context of your surroundings, then it’ll rapidly 3D print it (e.g., making a phone case that matches your wallet).

InstructMesh may also begin to incorporate physics simulations to model how your design may react to specific uses, such as whether a bowl breaks when dropped, and which materials would work best. The software might also integrate the more recent TRELLIS.2 to refine even smaller features in 3D models.

Stefanie Mueller, an associate professor of electrical engineering and computer science (EECS) and mechanical engineering at MIT, and a member of CSAIL, is a senior author on the paper. Faruqi and Mueller wrote the paper with Google researchers Ahmed Katary ’23; Fabian Manhardt; Vrushank Phadnis MEng ’13, PhD ’20; Ruofei Du; and Federico Tombari. Other co-authors were Northeastern University Assistant Professor Megan Hofmann along with several CSAIL colleagues: Demircan Tas SM ’24 and SMArchS ’24, a PhD student in EECS and architecture; former visiting researcher Theresa Hradilak; Ning Zhang ’25, a graduate student in EECS; postdoc Jiaji Li; and Martin Nisser SM ’19, PhD ’24.

The researchers’ work was supported, in part, by Google and the MIT-HPI Collaborative Research Program. They will present it at the ACM Symposium on User Interface Software and Technology in November.

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Media Advisory: Governor Healey, MIT President Kornbluth to Kick Off Festivities at MIT Future Fest

Massachusetts Governor Maura Healey and MIT President Sally Kornbluth will kick off MIT Future Fest, a new annual festival exploring the future of science, technology, art, and design, with “The Future Begins Here” panel, a celebration of Massachusetts innovation, talent and the bold questions shaping what comes next. The event will take place on Wednesday, September 30 at 3:30 PM at MIT’s Kresge Auditorium.

Curated and produced by the MIT Museum, the inaugural MIT Future Fest will take place across MIT’s campus from September 30–October 4, 2026. Governor Healy and President Kornbluth will be joined on the opening panel by Moderna co-founder and Flagship Pioneering founder and CEO Noubar Afeyan, MIT professor and entrepreneur Sangeeta Bhatia, and Bob Mumgaard, CEO and Co-Founder of Commonwealth Fusion Systems. Economic Development Secretary Eric Paley will moderate the discussion, which will explore how public, private, and educational institutions can work together to sustain talent pipelines, turn discovery into impact, and build the future

“Massachusetts is where the future is being invented, and MIT Future Fest is a chance to showcase our leadership in technology and design to the world,” said Governor Maura Healey. “From AI and robotics to clean energy and life sciences, the breakthroughs happening here are changing how we live and work. As Governor, I want Massachusetts to be the place where the best minds from around the world come to study, conduct research, start companies and scale their ideas. Our administration is investing in the talent, research and partnerships that make that possible, and we’re proud to launch MIT Future Fest with MIT.”

“The breakthrough discoveries that shape modern life came from decades of scientists and creators asking fundamental questions about how the world works. MIT Future Fest celebrates that same spirit of curiosity on mission," said MIT President Sally Kornbluth. "When you bring together engineers, inventors, artists, scientists, designers and entrepreneurs, you create the conditions for truly transformative innovation. This festival is an invitation to join that conversation, with the conviction that the future isn't something that happens to us—it's something we create together."

“The Future Beings Here” is one of more than 70 public talks, tours, performances, exhibitions, installations, and open laboratories included in the five-day program. Additional festival highlights and the full programming line-up are available at mitfuturefest.org. 

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Governor Healey and President Kornbluth launch MIT Future Fest

MIT Future Fest launched on Wednesday afternoon, featuring a visit from Massachusetts Governor Maura Healey before an opening panel at Kresge Auditorium.

Both Healey and MIT President Sally Kornbluth emphasized the power of curiosity and innovation during introductory remarks, while formally kicking off MIT Future Fest as a new kind of event that opens MIT’s doors to the world.

Spanning five days and featuring talks from leading MIT scholars, panel discussions, open labs, exhibitions, performances, screenings, and much more, MIT Future Fest adds up to a demonstration of campus research, teaching, thinking, and discovery.

“MIT and Massachusetts are known around the world as leaders in innovation,” Healey said. “Future Fest is a chance to celebrate that. But it’s also a chance to connect with each other. To learn from each other, and to imagine what comes next. In life sciences and biotech, robotics, advanced manufacturing, in energy and climate technology and quantum, and in the people who make it all happen.”  

In remarks preceding Healey’s talk, Kornbluth observed that “in a world as complex and interconnected as ours, we aim to invent the future. We need all the help we can get, and that’s why it’s so important to have all of you join us over the next five days in exploration, conversation, and curiosity.”

Future Fest also underscores that at MIT, as Kornbluth put it, “We feel a drive to explore, to understand, to solve, to invent, to design, all in service of society.” 

Since its founding, “MIT has long stood at the forefront of innovation and invention,” Healey noted. “‘The future starts here’ isn’t just a fitting theme for the next few days. It’s something we’ve been doing for the better part of 250 years in Massachusetts.”

Healey later appeared at an event about ocean sciences at the MIT Museum, whose staff have helped develop and organize MIT Future Fest. 

All told, MIT Future Fest features over 100 speakers at more than 50 events, among many other activities. The MIT Museum is free to the public during Future Fest; MIT’s newly opened Met Warehouse is hosting its first public events on Saturday; and Sunday features the Cambridge Science Carnival, a series of family activities. 

The remarks by Healey and Kornbluth were followed by a panel discussion, “The Future Begins Here,” featuring participants Noubar Afeyan PhD ’87, founder of Flagship Pioneering and co-founder of Moderna; Sangeeta Bhatia SM ’93, PhD ’97, the John J. and Dorothy Wilson Professor of Health Sciences and Technology and of Electrical Engineering and Computer Science at MIT, and director of MIT’s Marble Center for Cancer Nanomedicine; and Bob Mumgaard PhD ’15, CEO and co-founder of Commonwealth Fusion Systems. 

Massachusetts Economic Development Secretary Eric Paley moderated the wide-ranging discussion, which touched on the cutting-edge Massachusetts innovation ecosystem, the implications of artificial intelligence for research and industry, and more. 

The panelists noted that a confluence of ingredients — universities, other research institutions such as hospitals, venture capital, and more — has helped make Massachusetts the world leader in biotechnology and other forms of innovation. 

“You can’t be here and not feel like things that the rest of the world feel are not possible are possibly possible,” Afeyan said. “It’s really interesting how the environment makes you feel like you should also do something special.” He added that the various ecosystem elements have created a “critical mass” needed to sustain broad-ranging innovation. 

“This critical mass accumulated between the academic science, the hospital research, the entrepreneurial companies, large companies moved in, the government stepped in, state level, to try to help this community,” Afeyan observed. “It’s an inherent advantage of any ecosystem, it’s the co-location, it’s the connections.”

Mumgaard, whose company is building the first fusion power plant in the U.S., concurred that the combination of elements available in the state ecosystem is crucial for advanced innovation. 

“In many ways the challenge is simply scale,” Mumgaard said. “How do you get enough capital, how do you get enough smart people, how do you get enough people that are hard workers, how do you get the alignment from the institutions that can give you the permissions and tailwinds to be able to go and do that? And we did find that in Massachusetts.” 

He added: “You could not have really have built this company outside of Massachusetts.” 

For her part, Bhatia, a leader in developing nanoscale technologies that have made inroads in battling numerous forms of cancer, observed that part of the inspiration for her career came from visiting the MIT campus as a high school-age student.

“It was just that idea that you could engineer things, you could create instruments to improve human health, that started me on my journey,” Bhatia said. 

As a faculty member, she has helped found eight spinoff companies and helped direct an MIT study about how the Institute — which has already helped generate about 30,000 new companies — can do even more to produce startups and technology transfer. Ultimately, she has concluded, teaching researchers about the tools and skills they need to found companies can help generate even more productive networks of entrepreneurial activity.  

“We can be more intentional. We can create communities. … There are all kinds of ways to do more,” Bhatia said.

The panel discussion included reflections on AI and forecasts about the future of technology 20 years out, while ending with a reminder from Afeyan that, while the future is hard to forecast, it is at least partially shaped by people working consistently hard in pursuit of their goals. 

“We can envision the future a lot better than we can predict it,” Afeyan said, when asked to forecast the effects of technology in a couple of decades, near the end of the discussion.

Afeyan concluded: “My parting thought on this would be to say … I think you can either live in the present, do the things you do, and get the future you deserve, or you can envision the future you want, and do everything in service of that.”

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This game-playing AI is the new champ at Stratego

A new AI system that excels at challenging games with hidden information could someday help human decision-makers select ideal strategies to outfox opponents in complicated situations like military maneuvers.

Using advances in machine-learning, researchers from MIT, Carnegie Mellon University, New York University, and Stanford University developed an AI that defeated top-ranked human players of the board wargame Stratego by a large margin — something no AI system had been able to achieve. 

Stratego, a two-player game of imperfect information, in which the opponent’s piece identities remain hidden, is often used as a benchmark to test the strategic thinking abilities of powerful AI models.

To build their model, the researchers combined efficient training algorithms with new techniques tailored for calculated decision-making in hidden information settings. 

The AI system achieved greater performance at Stratego than the next best models, while being far cheaper and less computationally demanding to train. The system also outperformed top human players in other strategic games with different rules and designs, demonstrating how it can be generalized for a variety of use-cases.

The AI system could be adapted to help humans tackle many real-world problems with hidden information, such as business negotiations or cybersecurity. 

“In the kind of imperfect information tasks you would face in reality, you often don’t have the luxury of enumerating through all the possibilities. There are just too many. Having AI algorithms that are general purpose and can provably perform this challenging task so well is a big step forward,” says Gabriele Farina, an assistant professor in the Department of Electrical Engineering and Computer Science (EECS), principal investigator at the Laboratory for Information and Decision Systems (LIDS), and senior author of a paper on this AI system.

He is joined on the paper by lead author Samuel Sokota, a graduate student at Carnegie Mellon; Eugene Vinitsky and Zico Kolter, graduate students at NYU; Hengyuan Hu, a graduate student at Stanford; and Zhiyuan Fan, an EECS graduate student at MIT. The research appears today in Nature.

Hidden information

The world is full of imperfect information problems. 

In these interactions, some parties possess information others do not. For instance, traders in financial markets may not know the rationale behind the trades of others, while military forces likely don’t have full knowledge of enemy positions. 

With hidden information, the decisions parties make, as well as the decisions they choose not to make, are intertwined in such a way that it is extremely difficult to determine the best steps to take next.

“The more you bluff, the more your opponent expects it, and the less each bluff is worth. It’s not obvious how to reason about that,” Sokota explains. “It’s very different from a setting like chess, where the best move is still the best move no matter how often you’ve played it.”

Stratego is often used to model imperfect information situations. In this board wargame, which resembles military chess, players arrange 40 pieces on their side of a board and then move pieces across the board to capture their opponent’s flag. 

But the identity of all pieces remains secret until they collide, and then the lower-ranking piece is eliminated.

The possible piece configurations number more than 10 to the 66th power — an exponentially greater number than in chess — making Stratego extremely difficult for an AI system to play well. 

Past efforts, such as Google’s DeepMind, relied on sophisticated operations that were computationally demanding and costly. But even with millions of dollars in training costs, these models were still not strong enough to beat top human Stratego players.

“With Stratego, there is an explosion of possible universes you might have to deal with. AI techniques that were developed for games like poker definitely could not scale in this setting,” Farina says.

The MIT researchers set out to develop a full AI system that could achieve superhuman performance for less cost, which they called Ataraxos (a Greek word used to describe one who is unbothered or free from anxiety).

A two-pronged approach

To build Ataraxos, the researchers trained the model using a technique called self-play reinforcement learning. The model plays against itself many times to learn a strong “blueprint strategy” of how to excel at Stratego. 

They designed especially efficient algorithms, which enabled Ataraxos to learn much faster than prior methods while ensuring it didn’t get stuck trying to predict every possible move. This reduces training costs and boosts performance. 

“Our system reaches strictly higher playing strength than DeepNash (DeepMind’s system) while using less than one hundredth of the training examples and less than one thirtieth of the self-play games, indicating a massive improvement in efficiency,” says Farina.

During a game, Ataraxos uses the blueprint strategy as a starting point to set up the board and begin thinking about its next moves at each round of play. 

But before acting, it refines its choices on the fly using a technique called decision-time planning. The system employs a generative model that uses probabilities to estimate the likely identities of the opponent’s hidden pieces, then evaluates future choices before selecting the next move. 

“Rather than just guessing blindly, we use decision-time planning to find the most plausible state of the board. Using this generative model allows us to really zoom in on the specific board and opponent we are facing,” Farina says.

The innovative use of this generative model for decision-time planning was the missing piece that enabled Ataraxos to achieve superhuman performance.

Ataraxos beat the strongest Stratego player in the world by a record margin of 15-1-4 and achieved a 39-2 record against top human players at the Stratego world championship. “Ataraxos is good at calculating risk in a way that humans are not. A human might start freaking out if their most valuable piece is exposed, but the bot can be surprisingly composed. It doesn’t overcorrect and give away its secrets,” Farina says.

The researchers also adapted Ataraxos for other imperfect information games, including Barrage Stratego (a faster-paced variant with fewer pieces), Hanabi (a cooperative card game with many players), and Dou dizhu (a game in which two players cooperate against a third).

The system achieved superhuman performance in each instance, demonstrating the generality of this method.

In the future, the researchers want to build interpretability measures into Ataraxos so the system can explain its decision-making in a way that a human could understand. 

“Humans must have the final say in whether a recommendation is followed, so before adoption can happen, we need a way to audit the model’s decisions. We still have a long way to go, but I hope these algorithms can be the foundation for a lot more work to come,” Farina says.

This research is funded, in part, by the Office of Naval Research, the New York University Department of Civil and Urban Engineering, the C2SMART Center, the National Science Foundation, and a Schmidt Sciences AI2050 Early Career Fellowship.   

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Lung cancers can use two different mechanisms to evade KRAS-inhibiting drugs

About 25 percent of lung adenocarcinomas have mutations of the gene KRAS, which drives uncontrolled cell growth. In recent years, the FDA has approved two KRAS inhibitors to treat patients with KRAS mutations. While these drugs can work well initially, tumors almost always develop resistance to them.

Usually, resistance emerges because cells reactivate KRAS activity, through mutations that prevent drug binding or by increasing KRAS expression that overpowers the effects of the inhibitor. However, in a new study, MIT researchers have modeled an alternative mechanism that cancer cells can use to become resistant to KRAS inhibition.

The researchers found that in some cases, lung tumors undergo transformation from adenocarcinoma to squamous cell carcinoma. Both of these tumor types are commonly found in the lungs, but they are thought to  arise from different cells and have different genetic profiles.

When this transition occurs, tumor cells no longer require KRAS, and appear to turn on alternative signaling pathways that help them continue to grow. Ongoing work to identify those pathways may reveal targets for new drugs that could help prevent resistance to KRAS inhibitors.

“The main takeaway is that there seem to be different routes of resistance to KRAS inhibitors, and so we need to be thinking about how we can address this,” says Carrie Rodriguez, an MIT graduate student and one of the lead authors of the paper.

Nicolas Mathey-Andrews PhD ’25 is also a lead author of the study, which appears today in the journal Nature Genetics. The paper’s senior author is Tyler Jacks, the David H. Koch Professor of Biology and a member of MIT’s Koch Institute for Integrative Cancer Research.

Tissue transformation

The two FDA-approved KRAS inhibitors both target a mutation called KRAS-G12C. These drugs are approved only for use in patients whose tumors have failed to respond to other drugs, and these patients usually have cancer that has spread beyond the lungs.

KRAS inhibitors are effective in about 35 percent of the patients who receive them. However, in those cases, the tumors almost always end up becoming resistant by generating additional copies of the KRAS gene or finding other ways to turn on the MAP kinase signaling pathway, which is usually triggered by KRAS and stimulates cell growth.

“Resistance to targeted therapies is a very serious problem,” Rodriguez says. “Sometimes these KRAS inhibitors can hold cancers at bay, but most cases do end up relapsing.”

A 2021 study from researchers at Dana-Farber Cancer Institute, which analyzed tumors from 17 non-small cell lung cancer patients treated with KRAS-G12C inhibition, identified secondary resistance mutations in a majority of patients. In two of these patients, however, the researchers found that tumors transformed from adenocarcinomas to squamous cell carcinomas, but they did not harbor obvious resistance mutations.

Both adenocarcinomas and squamous cell carcinomas are classified as non-small cell lung cancers (NSCLCs), which are the most common type of primary lung cancer. Adenocarcinomas, the most common type of NSCLCs, often originate from the surfactant-producing cells that line the lungs, while squamous cell carcinomas originate in the cells that line the central airways of the lungs.

Mutations of KRAS are found much more frequently in adenocarcinomas than in squamous cell carcinomas

In this study, the researchers set out to model the factors that might drive the transition from adenocarcinomas to squamous cell carcinomas. To do that, they engineered a mouse lung cancer model to express the mutation that is targeted by the FDA-approved KRAS inhibitors. 

Following treatment with a KRAS-G12C inhibitor, tumors with genetic loss of Nkx2-1, which normally helps maintain alveolar epithelial identity, were able to undergo adeno-to-squamous transition. Turning on a transcription factor called DeltaNp63, which is overactive in many squamous cell carcinomas, also made this transition more likely. Another transcription factor known as SOX2 also helped stimulate the transition, but this gene could not initiate the transition on its own.

Paths to resistance

Tumors that underwent these tissue transformations did not acquire the mutations that typically boost KRAS expression in adenocarcinomas. Instead, KRAS signaling was shut off. The researchers hypothesize that these cells may turn on another signaling pathway that helps them to continue growing.

“There seem to be several different routes where you can get to squamous transformation, either through loss of lung-lineage-defining transcription factors, or overexpression of these squamous master regulators, SOX2 or DeltaNp63. Those resistant squamous tumors no longer respond to KRAS inhibition because they shut off the signaling or at least dampen it significantly,” Rodriguez says.

The researchers are now further exploring what happens to tumor cells as they transition to a squamous state, in hopes of identifying vulnerabilities that could be targeted with new drugs.

“Fundamentally this is a transition that’s poorly understood, and we were happy to see that we were able to model it,” Mathey-Andrews says. “Future directions that have an eye toward translation will utilize those models to understand the process and conditions by which histologic transformation occurs, and then also nominate potential targets downstream.”

The research was funded, in part, by the Koch Institute Support (core) Grant from the National Cancer Institute, a Ruth Kirschstein National Service Research Award, the National Institute of General Medical Sciences, and the Ludwig Center at MIT.

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Climate Action Learning Lab bridges research and policy for effective climate solutions

J-PAL North America, a regional office of MIT’s Abdul Latif Jameel Poverty Action Lab (J-PAL), convened the second cohort of the Climate Action Learning Lab this spring with 17 climate leaders from four U.S. government agencies and nonprofit organizations. Participants then engaged in four months of programming designed to strengthen their skills in generating and using evidence, applying research insights to their own programs, and identifying promising policy-relevant interventions for evaluation.

The Climate Action Learning Lab first emerged in 2025 as a response to an urgent need for rigorous research on programs that seek to improve resilience to climate-related hazards and support the transition to a low-carbon economy. By helping participants identify interventions and develop evaluation plans, the Learning Lab aims to generate evidence about which approaches are most effective, and for whom. 

“We have a unique opportunity to embed rigorous evaluation into promising programs as they are implemented in order to accurately measure their impacts on emissions reductions,” says Peter Christensen, scientific advisor of the J-PAL North America Environment, Energy, and Climate Change Sector. “By developing rigorous evaluations, Learning Lab participants can better understand the behavioral mechanisms that drive program impacts and cost-effectiveness, and build an evidence base to inform more effective policymaking.”

Following the success of last year’s Climate Action Learning Lab, which led to multiple research collaborations and the launch of two randomized evaluations, J-PAL North America recruited a second cohort of leaders representing four organizations: the City of Boston’s Sustainability Office, the Hawaii Climate Change Mitigation and Adaptation Commission, the Oregon Department of Environmental Quality, and the Electrification Coalition. 

From May through August, the cohort engaged in a set of offerings including training on impact evaluation, learning how to formulate research questions, and assessing the generalizability of the existing evidence to their own contexts. Participants had the opportunity to explore J-PAL resources, including the recently released Climate Action Evidence Review, which synthesizes existing evidence and highlights important gaps where more research is critical to inform effective, equitable climate action. 

“It was exciting to learn where the gaps in research are and where we have an opportunity to lead. The experience reinforced that we are addressing issues that have not been widely studied, and having access to researchers’ expertise was incredibly valuable,” says Ana Paola De La Vega, from the City of Boston’s Environment Department. Throughout the Learning Lab, the city explored a potential evaluation of its Boston Energy Saver program to better understand its impacts on energy cost savings and energy efficiency incentive uptake among small businesses.

Members of the Climate Action Learning Lab put theory into practice through personalized strategy sessions, where they examined potential programs for evaluation. Researchers from the J-PAL network joined select sessions to advise organizations on which programs to prioritize, considering factors such as research feasibility and existing evidence gaps. Each participating organization selected a target program and explored potential randomization approaches. 

“The Climate Action Learning Lab provided our team with a valuable opportunity to catalog our projects and better understand what makes a program ready for evaluation. It also helped us identify which initiatives are the strongest candidates for rigorous evaluation and how to prioritize them,” says Leah Laramee, Hawaii climate change mitigation and adaptation coordinator. During the Learning Lab, the team assessed three potential programs for evaluation and selected a rebate finder that connects residents with climate-related programs, with a focus on understanding its impact on program uptake, particularly among vulnerable communities.

In August, J-PAL North America hosted a virtual summit to celebrate Learning Lab participants as emerging champions for evidence in the climate space. During the event, cohort members presented their priority research questions and strategic evaluation plans and received feedback from researchers and peers. These presentations highlighted the progress made throughout the engagement and provided an opportunity to discuss next steps for advancing organizations’ evaluation plans beyond the Learning Lab.

“Overall, the Learning Lab has provided our team with a strong foundation to think critically about our own programming when applying for grants, setting up new projects, and determining how to assess impact from the beginning. This knowledge could ultimately help us determine what approaches the Electrification Coalition can take in future policies and programs,” says Ashley Blackwell, deputy director at the Electrification Coalition. 

Although formal Learning Lab programming has concluded, J-PAL North America will continue supporting organizations interested in launching a randomized evaluation through partnership development with researchers and potential funding opportunities. This Learning Lab cohort will join J-PAL North America’s Climate Action Community of Practice, alongside longtime partners and participants from the inaugural Learning Lab cohort. Together, Community of Practice members will continue to exchange ideas, build connections, and explore evidence-informed approaches to mitigation and adaptation strategies.

To learn more about J-PAL North America’s work in the energy, environment, and climate change sector, including our full range of activities, resources, and partnership opportunities, visit the Evidence for Climate Action Project webpage.

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Who we become when we talk to machines

Brian, a middle-aged financial consultant, spends his day sitting in front of three screens. Two of them involve his job. The third features a chatbot, which he has given a woman’s name and frequently uses. Brian spent years on the road for work earlier in his career, has never married, and recently broke up with a woman who said he was emotionally unavailable. What did Brian do, in response? He asked the chatbot if the woman had a point. 

“It’s an extraordinary moment,” writes MIT Professor Sherry Turkle, who interviewed Brian (not his real name) while conducting her research for her new book about chatbots. “Brian asks an object with no emotions to tell him if he is emotionally withholding: ‘Speak to me about what you cannot experience.’ As soon as he asks the program to talk about intimacy, he’s asking it to punch above its weight.”

And yet, this kind of thing seems to be happening a lot today. 

“People think the empathy of a machine is what empathy is, then turn away from the people in their lives because they’re not empathetic enough,” Turkle says. “We’re getting ourselves in a position where human beings are too much work, right at the moment when we have never needed other people more.”

After all, what is a chatbot? It’s a computer program predicting the most plausible next string of text in a conversation, based on massive amounts of data fed into it. 

“What a chatbot does is offer pretend empathy,” Turkle says. “After it tells you how much it loves you and how much it understands you, it doesn’t care if you kill yourself or cook some pasta.”

Sadly, chatbots have in fact been associated with high-profile cases of teen suicide as well, sometimes after teens get drawn into extensive dialogues with chat tools.

Turkle explores this terrain in a new book, “Artificial Intimacy: Who We Become When We Talk to Machines,” published today by Little, Brown and Company. After surveying evidence and conducting new research, she emphatically concludes that chatbot use, while it may often feel like a short-term salve, is broadly detrimental in terms of human development and social connectivity.

“We’re doing ourselves a tremendous disservice at every moment in the life cycle,” says Turkle, the Abby Rockefeller Mauzé Professor of the Social Studies of Science and Technology at MIT.

The inner history of technology

A sociologist and clinical psychologist by training, Turkle is a longtime faculty member in MIT’s Program in Science, Technology, and Society. In books such as “The Second Self” (1984), “Life on the Screen” (1997), and “Alone Together” (2011), she has evaluated the interplay of technology, psychology, and personal identity. In “Reclaiming Conversation” (2015), she documented the costs of texting and using social media. 

“I feel the story I’m telling is the inner history of technology,” Turkle says. “Not just what it does, but what it does to people.”

Turkle structures “Artificial Intimacy” around the stages of a human life and explores the implications of chatbots for each one. In her interviews with children, Turkle finds a persistent blurring of the line between chatbots, people, and other devices.

One 8-year-old uses the same phone to talk to their grandparents and to ChatGPT, regarding them all as “things you reach on your phone.” A weary graduate-student mother who uses a chatbot for bedtime stories says her daughter thinks the chatbot is “a person in the phone, absolutely.” 

In this sense, chatbots may be interfering with even the most basic childhood processes of distinguishing people from inanimate objects. Turkle finds many additional problems with the use of chatbots as ever-present entertainment for children, noting that a certain amount of time alone helps the development of imagination and inner resources. 

“Children can’t learn trust from a device that not only lies but doesn’t know when it lies,” Turkle writes. “They can’t develop the capacity for solitude that enables both a sense of self and the capacity for mutuality.”

All told, in affecting the ability of children to develop, the dangers of chatbots are “existential,” Turkle believes. 

Facing reality, but understanding the appeal

Adults don’t fare much better when they use chatbots heavily, Turkle says. “Artificial Intimacy” explores case after case of grown-ups who become dependent on chatbots as well: people going through divorces or estrangements who want dialogue, students looking for advice about applying to college or graduate school, workers who enlist ChatGPT to do assignments, and more. They start using chatbots, keep using chatbots, and before long seem less interested in human interaction, and less capable of it. 

“Once people are involved with a connection with a robot, they start to think that it’s alive, that it cares about them, that it loves them,” Turkle says. 

That means people can lose or fail to build their own capacities for new thought, and opt out of dealing with the real world in all its maddening-but-affirming complexity.

“We’re de-skilling ourselves as relational beings,” Turkle says. “We’re also de-skilling ourselves in work. We’re de-skilling ourselves in personal relationships. It’s across the board.” And speaking of a practice multiple people in the book have attempted, she says, “When we build chatbot avatars of dead relatives to keep them alive, we can lose our ability to mourn.”

We are not, in her estimation, doing the hard work of figuring other people out, seeing things from different points of view, and putting in the effort to build on those things and make society better.

“We’re starting to define being human as not doing the work,” Turkle says. 

For all of that, a considerable amount of “Artificial Intimacy” involves understanding why people engage with chatbots. After all, as Turkle writes in the book, “Chatbots always agree with us and affirm us. They always offer us their full, undivided attention.” And once that happens, things seem to just go from there. 

People, meanwhile, can be prickly, demanding, and moody. As Turkle says: “People say they prefer the chatbot because their husband or wife says, ‘Dear, you took out the garbage, but also do the dishes, and clean up the kitchen while you’re at it.’ And a chatbot just says, ‘Oh, you’re so wonderful.’” 

She adds: “This technology is offering something people really want, which is to feel less vulnerable. And it offers it over and over again. You don’t want to have to ask somebody out? Don’t want to offer condolences? At every opportunity, technology says, ‘Why don’t you do this thing that’s less hard.’” 

And as Turkle acknowledges in the book, there is a shortage of services such as mental health care providers in the U.S., where only about half of people have access to one, according to a federal government study she cites. Chatbots are helping to fill this void, for better or worse. 

Don’t fear the friction

Turkle also notes that the age of social media has likely led people to have fewer in-person friendships and interactions, a problem that chatbots are now aiming to address. 

“You take away people’s capacities, then you offer technology as the cure for the problems technology caused in the first place,” Turkle says.

In light of all this, given Turkle’s dim view of chatbots amid the spread of AI, what is actually to be done to restore human interaction? For starters, Turkle thinks, we need to face up to the idea that life is not frictionless — and that’s okay.

“Everything in the life cycle is about facing up to friction and fears and stress and tension, and understanding that friction is not a bad thing,” Turkle emphasizes. Developing the capacity to overcome difficulties is an essential part of life. In trying to sidestep the hard work of being social beings, she thinks, personal technology is enfeebling us.

Beyond that, Turkle envisions pushback against chatbots similar to the movement against, say, having phones in schools or letting young people use social media. 

“I hope my book is part of a larger and larger movement,” Turkle says. “I don’t want to be alone. I want to be part of a movement pushing back.”

Other writers in this domain have praised “Artificial Intimacy.” Journalist Nicholas Carr, author of “The Shallows,” has stated it “will help you avoid the profound but often hidden threats AI poses to you and your relationships.” Psychologist Jonathan Haidt of New York University, author of “The Anxious Generation,” has stated that Turkle’s “groundbreaking research and beautiful writing make her the most qualified member of Team Humanity to call us back to our senses, and to each other.” 

For her part, Turkle says, “I wanted to write a book that college students would read, that high school seniors, juniors would be able to read, that parents would pick up and not be intimidated by, that teachers would read.” 

And “Artificial Intimacy” offers a recurring question for those readers.

“If not a richer life in the real,” Turkle writes, “what’s our endgame?” The purpose of life, she underlines, is not to avoid it, but to tackle it head on. 

“It’s one thing if you say, my teen is texting too much,” Turkle says. “It’s very different if your 2-year-old is thinking a plushy toy with a chatbot inside is their best friend. Because you are getting into the intimate infrastructure of what makes a person develop. Social media came for our attention. Chatbots come for our capacity for attachment. That’s toxic on another level. What is the endgame? That the baby will prefer chatbots to people who are much more complicated and hard? Is that who we want to be?”

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Pressurized experiments could help wind farms generate more power

The world needs more wind energy. But anyone designing new wind turbines or trying to squeeze more power out of existing ones faces a stiff challenge testing new approaches. That’s because the atmosphere is a tough place for a controlled experiment.

Some researchers use wind tunnels to conduct tests, but scaled-down wind turbines in traditional wind tunnels can differ widely from conditions in the field. (Wind turbines are the largest rotating machines ever made.) The problem hampers not only development of better wind turbines, but also our understanding of basic questions like how much power to expect from a turbine when winds change direction.

In a new open access paper published in PNAS Nexus, researchers closed the gap between experiments in the field and the lab by using a wind tunnel that features high pressurization to simulate the flow physics in the atmosphere. With this approach, the researchers determined how the alignment of the turbine and its tip speed relative to the wind influence the power it generates, offering new insights into how to get more power from existing wind farms.

They also used the approach to validate a computationally lightweight model that engineers can use to test different turbine designs and wind farm control strategies.

Together, the researchers estimate that optimizing the turbine alignment relative to wind, the blade pitch angles, which control the airfoil’s angle of attack, and the tip speed relative to the wind could potentially result in tens of thousands of dollars per turbine every year in additional revenue.

“The immediate impact of this study is that we’ve now both improved and validated models that go into wind turbine control protocols for existing farms,” says Michael Howland, MIT’s Jeffrey Cheah Career Development Professor. “The bigger, medium-term impact, with a much larger upside, is this new experimental paradigm to rapidly prototype, validate simulation models, and test hypotheses about better designs and control strategies much faster than has been possible before.”

Joining Howland on the paper are first author John Kurelek, an assistant professor at Queen’s University; MIT PhD candidates Ilan Upfal and Kirby Heck; Queen’s University postdoc Supun Pieris; Penn State University researcher Alexander Piqué; and Princeton University Professor Marcus Hultmark.

Answers in the wind

Howland has spent years developing models to simulate wind farm performance and developing new techniques to increase their power output. In 2022, he showed that accounting for the wake of individual turbines when controlling the entire wind farm could significantly increase power output.

But that work required his research team to first conduct a lengthy field experiment that temporarily resulted in lowering a real wind farm’s power output by intentionally misaligning turbines from the wind for months to better understand their performance in misalignment.

“Wind energy is a uniquely challenging problem to study experimentally,” Howland says. “We want to test the effect of a certain change in isolation, but wind farms operate in chaotic, turbulent environments where the weather is constantly evolving. Wind turbines have to react to weather conditions that we have no control over, and that introduces complexities in identifying the impact of the imposed change we are studying. The field sits at this unique intersection between environmental flow, mechanics, aerodynamics, and meteorology.”

The difficulty of running experiments at real wind farms has left researchers and engineers unsure of how changes in the alignment between the wind and turbine or factors like the turbine’s tip speed relative to the wind change power output.

In fact, the researchers say many predictive models people use are built on the assumption that turbines are always perfectly perpendicular to the wind. That’s rarely the case in the real world, even with modern turbines that gradually adjust their angle in response to the wind’s rapid directional changes.

“People have been debating which models are best for understanding the output from these wind farms, but if you have nothing to compare them against, it’s very difficult to advance the field,” Hultmark says. “This paper tries to do both of those things.”

Hultmark’s research lab at Princeton has pioneered the study of scaled-down wind turbines in pressurized wind tunnels, which, as previous studies have shown, better reproduce large-scale turbines in the atmosphere because pressure makes air more dense, resulting in more inertia within the scaled laboratory environment. For the new study, the researchers used a turbine measuring 15 centimeters in diameter at varying pressures of up to 240 atmospheres.

“By pressurizing the chamber, we’re testing a turbine that is, all else being equal, 15 to 20 meters in diameter, with the ability to go up to 35 meters in diameter,” lead-author Kurelek explains. “That’s because we’re increasing the density by a factor of 100 to 220 times,” 

Kurelek sent the dimensions of the wind tunnel and wind turbine setup to Howland, who used them to calculate the aerodynamics, forces, and power production using a newly developed unified wind turbine model, which builds on previous work that developed a more general aerodynamic theory for wind turbines. The new model enables the researchers to simulate wind turbine performance across operating conditions without relying on empirical corrections that have historically been used in wind power models.

The researchers then ran a series of experiments in the tunnel over the course of several weeks, testing the turbine’s performance at different wind alignments and with different control strategies, to isolate how each factor affects performance.

They found power output could be significantly increased by adjusting the turbine’s tip speed based on its misalignment angle with the wind — a control strategy that is rarely employed in wind farms today but could offer a way to boost performance with minimal added costs.

“The big output of the experiments was clearly showing that new power maximums can be achieved when the turbine becomes misaligned with the wind through only changes to the tip speed,” Kurelek says.

Scaling the approach

The study served as validation for Howland’s model, which is fast enough to be run by engineers designing and operating wind turbines around the world using regular laptop computers.

“What we really want to know is if the turbines are always operating in some degree of misalignment with the wind, how should we control the turbine to get the maximum achievable power production?” Howland explains. “Our unified momentum model was able to make predictions of how to do this control a few years ago, and this is the first time we’e able to experimentally validate that model.”

Howland says validating models is only one part of the paper’s potential impact.

“This study also shows the huge opportunity to perform these high-throughput, controlled experiments in the pressurized facilities that Marcus and John work with, enabling us to achieve the right physics but in a time efficient and low-cost manner,” Howland says. “Right now, there’s a massive gap between idealized theoretical and simulation models and full-scale testing in extremely complicated field environments. Nothing is filling that gap except for these pressurized experiments. I hope this can be an enabler to investigate a huge range of unanswered wind energy questions in controlled environments.”

The work was supported in part by the Natural Sciences and Engineering Research Council of Canada; the National Science Foundation; and the MIT-GE Vernova Alliance.

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New formulation helps RNA vaccines withstand high temperatures

RNA vaccines, which have been proven effective against Covid-19, are now being developed for many other diseases, including cancer. One of the drawbacks to these vaccines is that they require ultracold storage, but researchers from MIT have found a promising way to overcome that limitation.

With help from an AI algorithm, the researchers tweaked the formulation surrounding the lipid nanoparticles that are typically used to deliver mRNA vaccines, making the vaccines more heat-resistant. Using this approach, they formulated vaccines that could remain stable even when stored at room temperature for up to a year, or at nearly 100 degrees Fahrenheit for two months.

When Covid-19 vaccines carried by these particles were administered to mice, they generated just as strong an immune response as an RNA Covid-19 vaccine similar to one developed by Moderna. By using the AI algorithm to predict the optimal formulations for the particles, the researchers were able to cut down the number of experiments they needed to do, which rapidly sped up the development process.

“The real beauty of this algorithm is that we can use it with small data sets,” says Ana Jaklenec, a principal investigator in MIT’s Koch Institute for Integrative Cancer Research. “It’s really hard to run thousands of experiments, so this algorithm allows us to more easily achieve formulations with features that we want — in this case, stability.”

Jaklenec and Robert Langer, the David H. Koch Institute Professor, are the senior authors of the paper, which appears today in Nature Biotechnology. Graduate student Jinbi Tian and postdoc Khanh Tran are the lead authors of the paper.

Stable vaccines

RNA is a highly fragile molecule, so researchers stabilize it with lipid nanoparticles (LNPs) that protect the RNA from degradation and help it get into cells. However, these RNA-LNP vaccines still need to be kept cold (-20 to -80 degrees Celsius), which makes it difficult to ship them to regions that don’t have cold-storage facilities available.

Making these vaccines more heat-tolerant would not only enable them to be distributed more widely, but could also help researchers develop new vaccines that could be administered through novel methods such as microneedle patches. These patches contain hundreds of vaccine-filled microneedles, which dissolve when the patch is applied to the skin, releasing the vaccine.

To create more stable RNA vaccines, researchers have experimented with adding a variety of excipients — sugars, salts, or polymers — to the LNPs. Jaklenec and Langer recently developed polymer-stabilized LNPs that can withstand higher temperatures, but those LNPs were slightly different from the FDA-approved formulations that were used for the Moderna and Pfizer Covid-19 vaccines. 

In their new paper, the researchers wanted to see if they could find a way to make those FDA-approved formulations more stable at high temperatures.

They began by reusing some of the excipients that had worked in their earlier efforts, but they were “really getting stuck,” Jaklenec says. “We were trying to use and screen excipients that we’ve previously used successfully to stabilize LNPs, but it just wasn’t working. It was really frustrating for the team.” 

To speed up their progress, the researchers decided to try a machine-learning approach. Working with researchers at MIT’s Computer Science and Artificial Intelligence Lab (CSAIL), they developed an algorithm that can make predictions based on very small datasets.

“We’d used our algorithms for various automated experimental design applications before, but never on a biological problem like vaccine stability,” says Mina Konaković Luković, an assistant professor of electrical engineering and computer science in MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL), who is also an author of the paper. “It was surprising to see how quickly the algorithm converged on a stable formulation — getting there in just a handful of iterations, rather than the exhaustive search that would normally be required.” 

The researchers used this algorithm to analyze nearly 50 FDA-approved excipients. For each excipient, the researchers first measured how well it stabilized RNA when incorporated into an LNP. They used these particles to deliver mRNA encoding a protein called firefly luciferase, which produces bioluminescence, into cells. By measuring how much light was emitted by the cells, the researchers could determine how effectively each excipient protected the mRNA.

The researchers chose five of the most promising excipients and used their AI algorithm to predict ratios of those excipients that would best stabilize LNPs similar to those used by Moderna. Based on those predictions, the researchers tested two formulations at a time in cells, fed those results back into the algorithm, and generated more predictions. After several rounds, they chose one formulation that appeared promising enough to test in animal studies.

This process took only a few weeks, much less than it would have taken without guidance from the AI algorithm.

“Before we implemented the AI algorithm, we spent several months testing different combinations and also doing the prescreening of all the excipients that we could find, but nothing would get us to 100 percent stability,” Tran says.

Robust immune responses

To test the heat resistance of their new LNP formulation, the researchers used the particles to package Covid-19 mRNA antigens, then dehydrated them using a process called vacuum drying. These particles were then stored at 37 degrees Celsius (98 degrees Fahrenheit) for two months, or at room temperature for one year. Mice that were vaccinated with these particles, even after long-term storage, showed equivalent immune responses to mice that received vaccines carried by LNPs similar to the original Moderna formulation.

The researchers also used their new heat-resistant formulation to create solid microneedle patches that could deliver a SARS-CoV-2 antigen. These patches generated an immune response similar to that produced by the injectable RNA vaccines.  

“Our approach broadens the application of not only mRNA vaccines, but also therapeutics or advanced drug-delivery platforms like controlled-release particles or microneedle patches, which requires the formulation to either be in solid state or to be stable at higher temperature,” Tian says. 

The researchers also showed that they could use their algorithm to stabilize other LNP formulations, including one similar to those used by Pfizer to deliver its Covid-19 vaccine. This formulation uses the same excipients as the one the MIT team developed for the Moderna LNP, but in a different ratio. For each LNP, once a heat-resistant formulation has been developed, it could be adapted to deliver any type of mRNA payload, the researchers say. 

The research was, in part, funded by the Gates Foundation.

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MIT students gain a humanist lens on technical innovation in Tulsa, Oklahoma

When MIT mechanical engineering student Daphne Wang arrived for her internship at the Muscogee Creek Nation Department of Health in Tulsa, Oklahoma last summer, she expected to be writing code. To her surprise, she found herself analyzing tribal history and the implications for technical innovation. 

“I learned so much that I think should be required curriculum for every single person in this country,” says Wang. “I think tech for good is genuinely getting out into communities and learning about people who aren't you, creating worldly perspectives that you ultimately can take into everything else that you do.”

Wang and fellow intern Lucy Sun, who is majoring in artificial intelligence and decision making, spent the summer supporting the development of the Muscogee Nation's first Pregnancy Risk Assessment Monitoring System (PRAMS) survey to capture maternal health data specific to Muscogee women. The project required completing literature reviews, analyzing datasets, and drafting survey questions, while considering issues of data sovereignty and governance structures specific to the Muscogee.

“It was this change of pace — 180 [degrees] from MIT, completely,” Wang reflects. At MIT, she says, course instructors routinely prepare students for big technical challenges, but there are fewer opportunities to “work with communities, [learn] how to think about the cultural and historical dimensions of the work, or how to consider the people who will be affected.” 

Wang’s supervisor, epidemiologist Breanna McNaughton-Long, was effusive about Wang and Sun’s engagement. “They were instrumental. They did so much work that I don't think we would have been able to do as quickly,” she says. “And they brought this sense that we were doing something that mattered.”

Experiential learning at the confluence of humanities and engineering 

Wang was one of 10 MIT undergraduates to participate in the PKG Center for Social Impact’s 2026 Code.Tulsa program. Now in its second year, Code.Tulsa is made possible by support from the Patrick J. McGovern Foundation and the George Kaiser Family Foundation. 

Students live at the University of Tulsa for the summer. They intern with the Muscogee and Cherokee nations, as well as local nonprofits Black Tech Street and Urban Coders Guild, completing AI, data science, and other technical projects. 

The PKG Center’s assistant dean for community-based programs, Vippy Yee, complements students’ professional experience with education on the historical and cultural significance of tech-based development in the Tulsa region from the perspective of local leaders. 

“As with all PKG Center programming, our aim is to help students integrate an engineer’s approach to problem-solving with a humanist lens on the nature of social challenges, and by extension interventions,” says Alison Badgett, the PKG Center’s director. 

“Getting to speak to people who were either very educated on the issues or have experienced them has been a massive help in reshaping the way that I think about social issues,” says Chenise Harper, an electrical engineering with computing major who interned with the Urban Coders Guild. 

Harper puts this dynamic candidly: “I hated history, but I learned a lot about why it is useful for making social change and how to go about researching it. I now feel a lot more confident that I can make an impact.”

A student’s vision for increasing STEM access

Code.Tulsa was the brainchild of sophomore Jack Carson, an electrical engineering and computer science (EECS) student who approached the PKG Center with the idea for Code.Tulsa as an incoming first-year student. Carson, who is from Tulsa and a member of the Cherokee Nation, saw firsthand that rural Native students who could benefit greatly from STEM education were unlikely to have access to it. Carson proposed developing a weeklong STEM camp for members of federally recognized tribes held at the University of Tulsa, with he and Code.Tulsa interns serving as instructors. 

Carson devised a nomination system to attract promising high school students, selecting 25 campers from 10 tribes out of 160 applications representing 25 Native nations. 

To develop the curriculum, Carson enlisted Harvard University student Allie Zong, whom he had met at Campus Preview Weekend. The Tulsa Advanced Sciences Camp (TASC) offers intensive, interactive track time in AI engineering, DNA technology, physics, and chemistry and energy. This is complemented by philosophical workshops to help students think more ambitiously and deliberately about what they can and should achieve in the near and long term. As Zong explains, “We teach them not knowledge, but curiosity, and the skills to teach themselves."

The TASC experience “kind of propelled me to self-study calculus,” says Alyssa Theofanidis, a rising high school senior from Houston who is a citizen of the Cherokee Nation. Theofanidis participated in the camp’s first year, returning this summer as a teaching assistant. Like many TASC campers, Theofanidis is eager to use her developing STEM expertise to benefit her Native community. 

TASC “got us to think 1,000 times more ambitiously about the impact we could have,” said another camper, who was inspired by guest speakers “like the nuclear fusion person at the top of their field,” referring to physicist Alexandra LeViness of MIT spinout Commonwealth Fusion Systems, who helped develop TASC’s chemistry and energy track. Campers were also inspired by “the different worldviews” of MIT interns. “I thought, maybe this is what MIT looks like,” said one camper, with several expressing the intent to apply to MIT as a result of the camp. 

Cherokee Nation Principal Chief Chuck Hoskin Jr. also delivered remarks at TASC, encouraging students as future leaders to take a public interest in technology. 

“Technology can be used for good, or it can be used for harm. Your generation has the opportunity to bend that arc toward something good,” Hoskin said. “It's a very special relationship that the Cherokee Nation has with MIT. As we reach out a hand in friendship, we have a hand reaching back. We are thankful for Cherokee citizen Jack Carson, a former secretary for the Cherokee Nation tribal youth council, for his leadership role in organizing this effort.”

Making a positive long-term social impact 

Like TASC campers, Code.Tulsa interns came away from the experience motivated to make a positive impact. While most MIT students won’t go on to full-time professional roles traditionally associated with social impact, PKG Center programming like Code.Tulsa helps students recognize they can promote the public interest no matter their career. As Elvis Chipiro, a junior in computer science and engineering, reflected after interning with the Cherokee Nation, “Social impact is not separate from mainstream technology; rather, it is embedded in the choices engineers make every day … Ultimately, meaningful social change is not driven by technology alone, but by people willing to design systems with empathy, responsibility, and inclusion at the center.”

For others, Code.Tulsa helps them reconnect with a sense of public purpose. “Remembering that … I could use my MIT education to help others was a big reason I applied to MIT in the first place,” says Harper. “But I forgot my own mission in the stress of school. Code.Tulsa really re-opened my eyes to why I am here.”

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A new technique could accelerate the development of RNA therapies

RNA vaccines and other nucleic acid therapeutics are typically packaged within fatty molecules known as lipid nanoparticles (LNPs). MIT researchers have now come up with a way to produce these particles much more quickly, and with more precise control over their size and shape.

This new process, which can be run automatically without any human intervention, could greatly speed up the development of new RNA and DNA therapeutics, the researchers say. 

“This method can help you determine what are the parameters that will generate specific size and shape attributes, before you take those particles and see which one will perform best,” says Cedric Devos, an MIT postdoc and one of the lead authors of the study. “It could be a quite powerful development tool.”

Current methods for designing new lipid nanoparticles often require time-consuming trial-and-error experiments, with limited investigation of desired particle size and shape. Tuning the size and shape of LNPs can open the possibility of targeting different organs and tissues.

“The size and shape of LNPs could not be reliably controlled by any previous production method. The problem may appear simple at first glance, but in reality it requires a deep understanding of lipid nanoparticle assembly,” says Allan Myerson, a professor of the practice in MIT’s Department of Chemical Engineering and the senior author of the new study.

MIT postdocs Aniket Udepurkar and Peter Sagmeister are also lead authors of the paper, which appears today in ACS Nano. 

More precise control

Vaccines based on mRNA work by delivering instructions to cells to produce a harmless version of a viral protein, which prompts the immune system to generate a response. However, if mRNA is injected on its own, it will be quickly broken down in the body.

“These are really a revolutionary type of therapeutics, but they need some kind of delivery vehicle to bring them to the right cells in the body,” Devos says.

For the mRNA Covid-19 vaccines and other mRNA therapeutics, scientists have used lipid nanoparticles for that packaging. LNPs usually consist of four components — an ionizable lipid, a phospholipid, cholesterol, and a lipid attached to a molecule of polyethylene glycol (PEG), which helps to stabilize the LNP.

To make the particles, two streams of fluid are mixed together at high speed. One consists of lipid molecules suspended in ethanol, and the other contains mRNA dissolved in an acidic buffer.

Those solutions aren’t mixed at equal flow rates, however. Instead, there is about three times more of the mRNA solution than the lipid solution. This unequal ratio helps promote the formation of lipid nanoparticles containing mRNA, but it doesn’t offer precise control over the size or shapes of the particles.

In a study published last year in ACS Nano, the MIT team showed that they could enable much better control of particle size by breaking the mixing process down into two steps. 

In the first step, mRNA and lipids are mixed together at equal flow rates. Then, after a short delay, more of the buffer is added, which halts the growth of the particles. Longer delays produce larger particles. 

“This gives you the ability to play around with the residence time, which is the time it takes between the first mixer and the second mixer. If you keep that residence time really long, it means your particles will grow a lot. If you keep it really short, you can keep them really small,” Devos says. “It gives you a lever over lipid nanoparticle manufacturing that wasn't available before.”

In that study, the researchers also showed that they could alter the shape of the particles. By changing the concentration of the buffer that they add in the second step, they were able to transform the particles from spheres to elongated particles that resemble avocados.

Both of these interventions — changing the delay residence time and changing the buffer composition — allow the researchers to control particle size and shape without otherwise altering the composition of the LNPs.

An automatic process

In the new ACS Nano paper, the researchers developed a way to automate the two-step mixing process. They also incorporated a commercially available dynamic light scattering device that can measure the sizes of the particles as they are formed.

The project also highlights the impact of MIT’s Undergraduate Research Opportunities Program (UROP). “Through this program, applied mathematics and computer science undergraduates Joy Ren, Sofiya Chubich, and Dylan Nguyen gained hands-on experience, learning how advanced software engineering can be integrated with chemical engineering to develop an automated platform for LNP process development,” Sagmeister says.

With this automated system, the researchers can specify a particle size, and the system will generate that size. It will also measure the resulting particles to make sure they’re the right size, and if not, adjust the delay time and other factors to steer them to the right size.

“The first paper really unlocked the new methodology to make lipid nanoparticles, to truly engineer them by size and shape,” Sagmeister says. “With the second study, we automate the whole process.”

The system can also produce particles of different shapes, but measuring those shapes has to be done outside of the automated system. 

Using this approach, the researchers were able to investigate how changing the inputs to the system affects the size and shapes of the particles, on a much faster timescale than currently possible. The researchers then used the data they gathered from these experiments to train a machine-learning model that can predict the combination of factors that will generate a particular size or shape.

With this method, it could be much easier for developers of RNA therapeutics to generate different sizes of particles to test them for a particular application. Controlling the size of a lipid nanoparticle is critical because the particle’s size determines where in the body it is most likely to end up. 

“If you make an LNP-based therapeutic with a target size of 150 nanometers, and one that is 70 nanometers, and everything else is the same, they will behave very differently,” Devos says.

The researchers have filed for a patent on their technology and are now working to commercialize it through a new company called BIZON Labs. Since receiving initial support through the Martin Trust Center for MIT Entrepreneurship’s Researcher 2 Entrepreneur (R2E) program, the team has also been accepted into MIT’s flagship accelerator program, delta v. The research was funded by the U.S. Food and Drug Administration and the Koch Institute Support (core) Grant from the National Cancer Institute. The work was carried out, in part, through the use of MIT.nano’s facilities.

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